Our printshop produces mostly books, booklets, manuals etc. Many of our customers want brochures, business cards, posters as well.
We migrated into the low quantity (200-5,000) full color pieces by purchasing a used Konica Minolta 8050. We had a bad experience with a lease and service agreement, so we've purchased our equipment ever since. Our first 8050 paid for itself in about 6 months time.
The Konica can bleed (print to the edge of the paper) an A3. For us that was a real bonus. We print business card stock, glossy stock, brochures and envelopes. We service our own equipment to keep it in top shape.
Many of our customers can not tell the difference between the Konica printer and our large offset printing presses.
You will want to find a unit with a Fiery RIP and a finisher (fold, bookletmake, stitch 3-hole punch). The large capacity tray (5,000 sheets) is not totally necessary as there are 3 trays in the unit itself.
Konica's NEW version of the 8050 is the 6500. But from all of the Problems with that machine (see Konica Forum) you should avoid it.
There are also the Konica BizHub 500 and 550. They are great machines too, just not as PRODUCTION oriented.